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3,3′-diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells

Increased consumption of cruciferous vegetables is associated with a reduced risk of developing prostate cancer. Indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) are phytochemicals derived from cruciferous vegetables that have shown promise in inhibiting prostate cancer in experimental models...

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Detalhes bibliográficos
Main Authors: Beaver, Laura M., Yu, Tian-Wei, Sokolowski, Elizabeth I., Williams, David E., Dashwood, Roderick H., Ho, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428467/
https://ncbi.nlm.nih.gov/pubmed/22800507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.07.007
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