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Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation()
The development of receptor tyrosine-kinase inhibitors (TKIs) was a major step forward in cancer treatment. However, the therapy with TKIs is limited by strong side effects and drug resistance. The aim of this study was the design of novel epidermal growth factor receptor (EGFR) inhibitors that are...
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| Gepubliceerd in: | Angew Chem Int Ed Engl |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336855/ https://ncbi.nlm.nih.gov/pubmed/25079700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403936 |
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