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Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs

[Image: see text] Although tyrosine kinase inhibitors (TKIs) have revolutionized cancer therapy in the past two decades, severe drawbacks such as strong adverse effects and drug resistance limit their clinical application. Prodrugs represent a valuable approach to overcoming these disadvantages by a...

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Détails bibliographiques
Publié dans:Inorg Chem
Auteurs principaux: Mathuber, Marlene, Schueffl, Hemma, Dömötör, Orsolya, Karnthaler, Claudia, Enyedy, Éva A., Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724630/
https://ncbi.nlm.nih.gov/pubmed/33222438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.0c03083
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