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Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation()
The development of receptor tyrosine-kinase inhibitors (TKIs) was a major step forward in cancer treatment. However, the therapy with TKIs is limited by strong side effects and drug resistance. The aim of this study was the design of novel epidermal growth factor receptor (EGFR) inhibitors that are...
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| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336855/ https://ncbi.nlm.nih.gov/pubmed/25079700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403936 |
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