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Subinhibitory Concentrations of LFF571 Reduce Toxin Production by Clostridium difficile
LFF571 is a novel semisynthetic thiopeptide antibacterial that is undergoing investigation for safety and efficacy in patients with moderate Clostridium difficile infections. LFF571 inhibits bacterial protein synthesis by interacting with elongation factor Tu (EF-Tu) and interrupting complex formati...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335859/ https://ncbi.nlm.nih.gov/pubmed/25512411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04436-14 |
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