Multicenter, Randomized Clinical Trial To Compare the Safety and Efficacy of LFF571 and Vancomycin for Clostridium difficile Infections

Clostridium difficile infection causes serious diarrheal disease. Although several drugs are available for treatment, including vancomycin, recurrences remain a problem. LFF571 is a semisynthetic thiopeptide with potency against C. difficile in vitro. In this phase 2 exploratory study, we compared t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Mullane, Kathleen, Lee, Christine, Bressler, Adam, Buitrago, Martha, Weiss, Karl, Dabovic, Kristina, Praestgaard, Jens, Leeds, Jennifer A., Blais, Johanne, Pertel, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325808/
https://ncbi.nlm.nih.gov/pubmed/25534727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04251-14
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