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Pharmacokinetics of LFF571 and Vancomycin in Patients with Moderate Clostridium difficile Infections

Clostridium difficile infection causes diarrheal disease with potentially fatal complications. Although treatments are available, including vancomycin, metronidazole, and fidaxomicin, the recurrence of disease after therapy remains a problem. LFF571 is a novel thiopeptide antibacterial that shows in...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Bhansali, Suraj G., Mullane, Kathleen, Ting, Lillian S. L., Leeds, Jennifer A., Dabovic, Kristina, Praestgaard, Jens, Pertel, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325791/
https://ncbi.nlm.nih.gov/pubmed/25534724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04252-14
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