Pharmacokinetics of LFF571 and Vancomycin in Patients with Moderate Clostridium difficile Infections

Clostridium difficile infection causes diarrheal disease with potentially fatal complications. Although treatments are available, including vancomycin, metronidazole, and fidaxomicin, the recurrence of disease after therapy remains a problem. LFF571 is a novel thiopeptide antibacterial that shows in...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Bhansali, Suraj G., Mullane, Kathleen, Ting, Lillian S. L., Leeds, Jennifer A., Dabovic, Kristina, Praestgaard, Jens, Pertel, Peter
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325791/
https://ncbi.nlm.nih.gov/pubmed/25534724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04252-14
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