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Efficacy of LFF571 in a Hamster Model of Clostridium difficile Infection

LFF571 is a novel semisynthetic thiopeptide antibiotic with potent activity against a variety of Gram-positive pathogens, including Clostridium difficile. In vivo efficacy of LFF571 was compared to vancomycin in a hamster model of C. difficile infection (CDI). Infection was induced in Golden Syrian...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Trzasko, Anna, Leeds, Jennifer A., Praestgaard, Jens, LaMarche, Matthew J., McKenney, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421564/
https://ncbi.nlm.nih.gov/pubmed/22644020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06355-11
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