Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability

GLP and G9a are major H3K9 dimethylases and are essential for mouse early embryonic development. GLP and G9a both harbor ankyrin repeat domains that are capable of binding H3K9 methylation. However, the functional significance of their recognition of H3K9 methylation is unknown. Here, we report that...

詳細記述

保存先:
書誌詳細
出版年:Genes Dev
主要な著者: Liu, Nan, Zhang, Zhuqiang, Wu, Hui, Jiang, Yonghua, Meng, Lingjun, Xiong, Jun, Zhao, Zuodong, Zhou, Xiaohua, Li, Jia, Li, Hong, Zheng, Yong, Chen, She, Cai, Tao, Gao, Shaorong, Zhu, Bing
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2015
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335294/
https://ncbi.nlm.nih.gov/pubmed/25637356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.254425.114
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