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Transcriptional Repressive H3K9 and H3K27 Methylations Contribute to DNMT1-Mediated DNA Methylation Recovery

DNA methylation and histone modifications are two major epigenetic events regulating gene expression and chromatin structure, and their alterations are linked to human carcinogenesis. DNA methylation plays an important role in tumor suppressor gene inactivation, and can be revised by DNA methylation...

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Detalles Bibliográficos
Main Authors: Wong, Chun-Ming, Wong, Carmen Chak-Lui, Ng, Yeung-Lam, Au, Sandy Leung-Kuen, Ko, Frankie Chi-Fat, Ng, Irene Oi-Lin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035659/
https://ncbi.nlm.nih.gov/pubmed/21347439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016702
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