REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

DNA polymerase zeta (pol ζ) is exceptionally important for controlling mutagenesis and genetic instability. REV3L comprises the catalytic subunit, while REV7 (MAD2L2) is considered an accessory subunit. However, it has not been established that the role of REV7 in DNA damage tolerance is necessarily...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Tomida, Junya, Takata, Kei-ichi, Lange, Sabine S., Schibler, Andria C., Yousefzadeh, Matthew J., Bhetawal, Sarita, Dent, Sharon Y.R., Wood, Richard D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333420/
https://ncbi.nlm.nih.gov/pubmed/25567983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1385
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