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REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ
DNA polymerase zeta (pol ζ) is exceptionally important for controlling mutagenesis and genetic instability. REV3L comprises the catalytic subunit, while REV7 (MAD2L2) is considered an accessory subunit. However, it has not been established that the role of REV7 in DNA damage tolerance is necessarily...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nucleic Acids Res |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333420/ https://ncbi.nlm.nih.gov/pubmed/25567983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1385 |
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