REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

DNA polymerase zeta (pol ζ) is exceptionally important for controlling mutagenesis and genetic instability. REV3L comprises the catalytic subunit, while REV7 (MAD2L2) is considered an accessory subunit. However, it has not been established that the role of REV7 in DNA damage tolerance is necessarily...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Tomida, Junya, Takata, Kei-ichi, Lange, Sabine S., Schibler, Andria C., Yousefzadeh, Matthew J., Bhetawal, Sarita, Dent, Sharon Y.R., Wood, Richard D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333420/
https://ncbi.nlm.nih.gov/pubmed/25567983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1385
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