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DNA polymerases and cancer

There are fifteen different DNA polymerases encoded in mammalian genomes, which are specialized for replication, repair or the tolerance of DNA damage. New evidence is emerging for lesion-specific and tissue-specific functions of DNA polymerases. Many point mutations that occur in cancer cells arise...

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Detalhes bibliográficos
Main Authors: Lange, Sabine S., Takata, Kei-ichi, Wood, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739438/
https://ncbi.nlm.nih.gov/pubmed/21258395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2998
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