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DNA polymerases and cancer
There are fifteen different DNA polymerases encoded in mammalian genomes, which are specialized for replication, repair or the tolerance of DNA damage. New evidence is emerging for lesion-specific and tissue-specific functions of DNA polymerases. Many point mutations that occur in cancer cells arise...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739438/ https://ncbi.nlm.nih.gov/pubmed/21258395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2998 |
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