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DNA polymerases and cancer

There are fifteen different DNA polymerases encoded in mammalian genomes, which are specialized for replication, repair or the tolerance of DNA damage. New evidence is emerging for lesion-specific and tissue-specific functions of DNA polymerases. Many point mutations that occur in cancer cells arise...

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Autores principales: Lange, Sabine S., Takata, Kei-ichi, Wood, Richard D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739438/
https://ncbi.nlm.nih.gov/pubmed/21258395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2998
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