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FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1‐defective cells

To exploit vulnerabilities of tumors, it is urgent to identify associated defects in genome maintenance. One unsolved problem is the mechanism of regulation of DNA double‐strand break repair by REV7 in complex with 53BP1 and RIF1, and its influence on repair pathway choice between homologous recombi...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Tomida, Junya, Takata, Kei‐ichi, Bhetawal, Sarita, Person, Maria D, Chao, Hsueh‐Ping, Tang, Dean G, Wood, Richard D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003645/
https://ncbi.nlm.nih.gov/pubmed/29789392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899543
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