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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details

Transcriptional fidelity, which prevents the misincorporation of incorrect nucleoside monophosphates in RNA, is essential for life. Results from molecular dynamics (MD) simulations of eukaryotic RNA polymerase (RNAP) II and bacterial RNAP with experimental data suggest that fidelity may involve as m...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Wang, Beibei, Opron, Kristopher, Burton, Zachary F., Cukier, Robert I., Feig, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333413/
https://ncbi.nlm.nih.gov/pubmed/25550432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1370
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