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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details
Transcriptional fidelity, which prevents the misincorporation of incorrect nucleoside monophosphates in RNA, is essential for life. Results from molecular dynamics (MD) simulations of eukaryotic RNA polymerase (RNAP) II and bacterial RNAP with experimental data suggest that fidelity may involve as m...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333413/ https://ncbi.nlm.nih.gov/pubmed/25550432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1370 |
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