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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details

Transcriptional fidelity, which prevents the misincorporation of incorrect nucleoside monophosphates in RNA, is essential for life. Results from molecular dynamics (MD) simulations of eukaryotic RNA polymerase (RNAP) II and bacterial RNAP with experimental data suggest that fidelity may involve as m...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Wang, Beibei, Opron, Kristopher, Burton, Zachary F., Cukier, Robert I., Feig, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333413/
https://ncbi.nlm.nih.gov/pubmed/25550432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1370
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