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Energetic and Structural Details of the Trigger-Loop Closing Transition in RNA Polymerase II

An evolutionarily conserved element in RNA polymerase II, the trigger loop (TL), has been suggested to play an important role in the elongation rate, fidelity of selection of the matched nucleoside triphosphate (NTP), catalysis of transcription elongation, and translocation in both eukaryotes and pr...

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Autors principals: Wang, Beibei, Predeus, Alexander V., Burton, Zachary F., Feig, Michael
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736665/
https://ncbi.nlm.nih.gov/pubmed/23931324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.060
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