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The RNA polymerase trigger loop functions in all three phases of the transcription cycle

The trigger loop (TL) forms a conserved element in the RNA polymerase active centre that functions in the elongation phase of transcription. Here, we show that the TL also functions in transcription initiation and termination. Using recombinant variants of RNA polymerase from Pyrococcus furiosus and...

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Main Authors: Fouqueau, Thomas, Zeller, Mirijam E., Cheung, Alan C., Cramer, Patrick, Thomm, Michael
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737540/
https://ncbi.nlm.nih.gov/pubmed/23737452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt433
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