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The RNA polymerase trigger loop functions in all three phases of the transcription cycle

The trigger loop (TL) forms a conserved element in the RNA polymerase active centre that functions in the elongation phase of transcription. Here, we show that the TL also functions in transcription initiation and termination. Using recombinant variants of RNA polymerase from Pyrococcus furiosus and...

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Detalhes bibliográficos
Main Authors: Fouqueau, Thomas, Zeller, Mirijam E., Cheung, Alan C., Cramer, Patrick, Thomm, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737540/
https://ncbi.nlm.nih.gov/pubmed/23737452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt433
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