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A novel intermediate in transcription initiation by human mitochondrial RNA polymerase
The mitochondrial genome is transcribed by a single-subunit T7 phage-like RNA polymerase (mtRNAP), structurally unrelated to cellular RNAPs. In higher eukaryotes, mtRNAP requires two transcription factors for efficient initiation—TFAM, a major nucleoid protein, and TFB2M, a transient component of mt...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973326/ https://ncbi.nlm.nih.gov/pubmed/24393772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1356 |
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