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Structural basis of mitochondrial transcription initiation

Transcription in human mitochondria is driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP). Despite of its critical role in both expression and replication of the mitochondrial genome, transcription initiation by mtRNAP remains poorly understood. Here we report crystal structures of...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Hillen, Hauke S., Morozov, Yaroslav I., Sarfallah, Azadeh, Temiakov, Dmitry, Cramer, Patrick
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590061/
https://ncbi.nlm.nih.gov/pubmed/29149603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.036
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