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Structural basis of mitochondrial transcription initiation

Transcription in human mitochondria is driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP). Despite of its critical role in both expression and replication of the mitochondrial genome, transcription initiation by mtRNAP remains poorly understood. Here we report crystal structures of...

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Dettagli Bibliografici
Pubblicato in:Cell
Autori principali: Hillen, Hauke S., Morozov, Yaroslav I., Sarfallah, Azadeh, Temiakov, Dmitry, Cramer, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590061/
https://ncbi.nlm.nih.gov/pubmed/29149603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.036
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