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Structural basis of mitochondrial transcription initiation

Transcription in human mitochondria is driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP). Despite of its critical role in both expression and replication of the mitochondrial genome, transcription initiation by mtRNAP remains poorly understood. Here we report crystal structures of...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Hillen, Hauke S., Morozov, Yaroslav I., Sarfallah, Azadeh, Temiakov, Dmitry, Cramer, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590061/
https://ncbi.nlm.nih.gov/pubmed/29149603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.036
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