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Structural basis of mitochondrial transcription initiation

Transcription in human mitochondria is driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP). Despite of its critical role in both expression and replication of the mitochondrial genome, transcription initiation by mtRNAP remains poorly understood. Here we report crystal structures of...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Hillen, Hauke S., Morozov, Yaroslav I., Sarfallah, Azadeh, Temiakov, Dmitry, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590061/
https://ncbi.nlm.nih.gov/pubmed/29149603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.036
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