Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases

RNA cleavage by bacterial RNA polymerase (RNAP) has been implicated in transcriptional proofreading and reactivation of arrested transcription elongation complexes but its molecular mechanism is less understood than the mechanism of nucleotide addition, despite both reactions taking place in the sam...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Esyunina, Daria, Turtola, Matti, Pupov, Danil, Bass, Irina, Klimašauskas, Saulius, Belogurov, Georgiy, Kulbachinskiy, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756841/
https://ncbi.nlm.nih.gov/pubmed/26733581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1521
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