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Conserved functions of the trigger loop and Gre factors in RNA cleavage by bacterial RNA polymerases

RNA cleavage by RNA polymerase (RNAP) is the central step in co-transcriptional RNA proofreading. Bacterial RNAPs were proposed to rely on the same mobile element of the active site, the trigger loop (TL), for both nucleotide addition and RNA cleavage. RNA cleavage can also be stimulated by universa...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Miropolskaya, Nataliya, Esyunina, Daria, Kulbachinskiy, Andrey
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
RNA
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399121/
https://ncbi.nlm.nih.gov/pubmed/28242762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.766592
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