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Role of the trigger loop in translesion RNA synthesis by bacterial RNA polymerase

DNA lesions can severely compromise transcription and block RNA synthesis by RNA polymerase (RNAP), leading to subsequent recruitment of DNA repair factors to the stalled transcription complex. Recent structural studies have uncovered molecular interactions of several DNA lesions within the transcri...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Agapov, Aleksei, Ignatov, Artem, Turtola, Matti, Belogurov, Georgiy, Esyunina, Daria, Kulbachinskiy, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363142/
https://ncbi.nlm.nih.gov/pubmed/32439804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011844
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