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Interplay between the trigger loop and the F loop during RNA polymerase catalysis

The trigger loop (TL) in the RNA polymerase (RNAP) active center plays key roles in the reactions of nucleotide addition and RNA cleavage catalyzed by RNAP. The adjacent F loop (FL) was proposed to contribute to RNAP catalysis by modulating structural changes in the TL. Here, we investigate the inte...

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Detalhes bibliográficos
Main Authors: Miropolskaya, Nataliya, Esyunina, Daria, Klimašauskas, Saulius, Nikiforov, Vadim, Artsimovitch, Irina, Kulbachinskiy, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874190/
https://ncbi.nlm.nih.gov/pubmed/24089145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt877
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