Interplay between the trigger loop and the F loop during RNA polymerase catalysis

The trigger loop (TL) in the RNA polymerase (RNAP) active center plays key roles in the reactions of nucleotide addition and RNA cleavage catalyzed by RNAP. The adjacent F loop (FL) was proposed to contribute to RNAP catalysis by modulating structural changes in the TL. Here, we investigate the inte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Miropolskaya, Nataliya, Esyunina, Daria, Klimašauskas, Saulius, Nikiforov, Vadim, Artsimovitch, Irina, Kulbachinskiy, Andrey
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Nucleic Acid Enzymes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874190/
https://ncbi.nlm.nih.gov/pubmed/24089145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt877
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