Multiple roles of the RNA polymerase β′ SW2 region in transcription initiation, promoter escape, and RNA elongation

Interactions of RNA polymerase (RNAP) with nucleic acids must be tightly controlled to ensure precise and processive RNA synthesis. The RNAP β′-subunit Switch-2 (SW2) region is part of a protein network that connects the clamp domain with the RNAP body and mediates opening and closing of the active...

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Bibliografiska uppgifter
Huvudupphovsmän: Pupov, Danil, Miropolskaya, Nataliya, Sevostyanova, Anastasiya, Bass, Irina, Artsimovitch, Irina, Kulbachinskiy, Andrey
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943606/
https://ncbi.nlm.nih.gov/pubmed/20457751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq355
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