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Mutations in the CRE pocket of bacterial RNA polymerase affect multiple steps of transcription

During transcription, the catalytic core of RNA polymerase (RNAP) must interact with the DNA template with low-sequence specificity to ensure efficient enzyme translocation and RNA extension. Unexpectedly, recent structural studies of bacterial promoter complexes revealed specific interactions betwe...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Petushkov, Ivan, Pupov, Danil, Bass, Irina, Kulbachinskiy, Andrey
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499132/
https://ncbi.nlm.nih.gov/pubmed/25990734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv504
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