Structural Basis of Transcription Initiation by Bacterial RNA Polymerase Holoenzyme

The bacterial RNA polymerase (RNAP) holoenzyme containing σ factor initiates transcription at specific promoter sites by de novo RNA priming, the first step of RNA synthesis where RNAP accepts two initiating ribonucleoside triphosphates (iNTPs) and performs the first phosphodiester bond formation. W...

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Hlavní autoři: Basu, Ritwika S., Warner, Brittany A., Molodtsov, Vadim, Pupov, Danil, Esyunina, Daria, Fernández-Tornero, Carlos, Kulbachinskiy, Andrey, Murakami, Katsuhiko S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148879/
https://ncbi.nlm.nih.gov/pubmed/24973216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.584037
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