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Structural basis of ribosomal RNA transcription regulation

Ribosomal RNA (rRNA) is most highly expressed in rapidly growing bacteria and is drastically downregulated under stress conditions by the global transcriptional regulator DksA and the alarmone ppGpp. Here, we determined cryo-electron microscopy structures of the Escherichia coli RNA polymerase (RNAP...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shin, Yeonoh, Qayyum, M. Zuhaib, Pupov, Danil, Esyunina, Daria, Kulbachinskiy, Andrey, Murakami, Katsuhiko S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822876/
https://ncbi.nlm.nih.gov/pubmed/33483500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20776-y
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