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Structural basis of ribosomal RNA transcription regulation
Ribosomal RNA (rRNA) is most highly expressed in rapidly growing bacteria and is drastically downregulated under stress conditions by the global transcriptional regulator DksA and the alarmone ppGpp. Here, we determined cryo-electron microscopy structures of the Escherichia coli RNA polymerase (RNAP...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822876/ https://ncbi.nlm.nih.gov/pubmed/33483500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20776-y |
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