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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details

Transcriptional fidelity, which prevents the misincorporation of incorrect nucleoside monophosphates in RNA, is essential for life. Results from molecular dynamics (MD) simulations of eukaryotic RNA polymerase (RNAP) II and bacterial RNAP with experimental data suggest that fidelity may involve as m...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Wang, Beibei, Opron, Kristopher, Burton, Zachary F., Cukier, Robert I., Feig, Michael
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333413/
https://ncbi.nlm.nih.gov/pubmed/25550432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1370
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