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The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation

The bridge α-helix in the β′ subunit of RNA polymerase (RNAP) borders the active site and may have roles in catalysis and translocation. In Escherichia coli RNAP, a bulky hydrophobic segment near the N-terminal end of the bridge helix is identified (β′ 772-YFI-774; the YFI motif). YFI is located at...

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Bibliografiset tiedot
Päätekijät: Nedialkov, Yuri A., Opron, Kristopher, Assaf, Fadi, Artsimovitch, Irina, Kireeva, Maria L., Kashlev, Mikhail, Cukier, Robert I., Nudler, Evgeny, Burton, Zachary F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619131/
https://ncbi.nlm.nih.gov/pubmed/23202476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.11.005
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