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The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation
The bridge α-helix in the β′ subunit of RNA polymerase (RNAP) borders the active site and may have roles in catalysis and translocation. In Escherichia coli RNAP, a bulky hydrophobic segment near the N-terminal end of the bridge helix is identified (β′ 772-YFI-774; the YFI motif). YFI is located at...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619131/ https://ncbi.nlm.nih.gov/pubmed/23202476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.11.005 |
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