RNA Polymerase II with Open and Closed Trigger Loops: Active Site Dynamics and Nucleic Acid Translocation

RNA polymerase II is the central eukaryotic enzyme in transcription from DNA to RNA. The dynamics of RNA polymerase II is described from molecular-dynamics simulations started from two crystal structures with open and closed trigger loop (TL) forms. Dynamic transitions between neutral and forward tr...

Full description

Saved in:
Bibliographic Details
Main Authors: Feig, Michael, Burton, Zachary F.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Nucleic Acid
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956212/
https://ncbi.nlm.nih.gov/pubmed/20959099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.010
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items