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Closing and opening of the RNA polymerase trigger loop

The RNA polymerase (RNAP) trigger loop (TL) is a mobile structural element of the RNAP active center that, based on crystal structures, has been proposed to cycle between an “unfolded”/“open” state that allows an NTP substrate to enter the active center and a “folded”/“closed” state that holds the N...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mazumder, Abhishek, Lin, Miaoxin, Kapanidis, Achillefs N., Ebright, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355006/
https://ncbi.nlm.nih.gov/pubmed/32571927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920427117
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