Loading...
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
In the current model of DNA SSBR, PARP1 is regarded as the sensor of single-strand breaks (SSBs). However, biochemical studies have implicated LIG3 as another possible SSB sensor. Using a laser micro-irradiation protocol that predominantly generates SSBs, we were able to demonstrate that PARP1 is di...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333375/ https://ncbi.nlm.nih.gov/pubmed/25539916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1307 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|