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Polycomb repressive complex 2 contributes to DNA double-strand break repair

Polycomb protein histone methyltransferase, enhancer of Zeste homolog 2 (EZH2), is frequently overexpressed in human malignancy and is implicated in cancer cell proliferation and invasion. However, it is largely unknown whether EZH2 has a role in modulating the DNA damage response. Here, we show tha...

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Detalhes bibliográficos
Main Authors: Campbell, Stuart, Ismail, Ismail Hassan, Young, Leah C, Poirier, Guy G, Hendzel, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865057/
https://ncbi.nlm.nih.gov/pubmed/23907130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25795
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