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The PBAF chromatin remodeling complex represses transcription and promotes rapid repair at DNA double-strand breaks
Transcription in the vicinity of DNA double-strand breaks (DSBs) is suppressed via a process involving ataxia telangiectasia mutated protein (ATM) and H2AK119 ubiquitylation.(1) We discuss recent findings that components of the Polybromo and Brahma-related gene 1 (BRG1)-associated factor (PBAF) remo...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905236/ https://ncbi.nlm.nih.gov/pubmed/27308404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970072 |
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