A carregar...
Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
DNA double-strand breaks (DSBs) are fatal DNA lesions and activate a rapid DNA damage response. However, the earliest stage of DSB sensing remains elusive. Here, we report that PARP1 and the Ku70/80 complex localize to DNA lesions considerably earlier than other DSB sensors. Using super-resolved flu...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909444/ https://ncbi.nlm.nih.gov/pubmed/29447383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky088 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|