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A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

While active tuberculosis (TB) is a treatable disease, many complex factors prevent its global elimination. Part of the difficulty in developing optimal therapies is the large design space of antibiotic doses, regimens and combinations. Computational models that capture the spatial and temporal dyna...

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Detalles Bibliográficos
Publicado en:J Theor Biol
Main Authors: Pienaar, Elsje, Cilfone, Nicholas A., Lin, Philana Ling, Dartois, Véronique, Mattila, Joshua T., Butler, Russ, Flynn, JoAnne L., Kirschner, Denise E., Linderman, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332617/
https://ncbi.nlm.nih.gov/pubmed/25497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.11.021
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