Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), induces formation of granulomas, structures in which immune cells and bacteria colocalize. Macrophages are among the most abundant cell types in granulomas and have been shown to serve as both critical bactericidal cells and targe...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Flynn, JoAnne L., Kirschner, Denise E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288886/
https://ncbi.nlm.nih.gov/pubmed/25368116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02494-14
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