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Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), induces formation of granulomas, structures in which immune cells and bacteria colocalize. Macrophages are among the most abundant cell types in granulomas and have been shown to serve as both critical bactericidal cells and targe...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Flynn, JoAnne L., Kirschner, Denise E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288886/
https://ncbi.nlm.nih.gov/pubmed/25368116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02494-14
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