Computational Modeling Predicts Interleukin-10 Control of Lesion Sterilization By Balancing Early Host-Immunity-Mediated Antimicrobial Responses With Caseation During Mycobacterium tuberculosis Infection

Although almost a third of the world’s population is infected with the bacterial pathogen Mycobacterium tuberculosis (Mtb), our understanding of the functions of many immune factors involved in fighting infection is limited. Determining the role of the immunosuppressive cytokine interleukin-10 (IL-1...

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Bibliographic Details
Published in:J Immunol
Main Authors: Cilfone, Nicholas A., Ford, Christopher B., Marino, Simeone, Mattila, Joshua T., Gideon, Hannah P., Flynn, JoAnne L., Kirschner, Denise E., Linderman, Jennifer J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283220/
https://ncbi.nlm.nih.gov/pubmed/25512604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400734
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