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A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

While active tuberculosis (TB) is a treatable disease, many complex factors prevent its global elimination. Part of the difficulty in developing optimal therapies is the large design space of antibiotic doses, regimens and combinations. Computational models that capture the spatial and temporal dyna...

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Detalhes bibliográficos
Publicado no:J Theor Biol
Main Authors: Pienaar, Elsje, Cilfone, Nicholas A., Lin, Philana Ling, Dartois, Véronique, Mattila, Joshua T., Butler, Russ, Flynn, JoAnne L., Kirschner, Denise E., Linderman, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332617/
https://ncbi.nlm.nih.gov/pubmed/25497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.11.021
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