A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

While active tuberculosis (TB) is a treatable disease, many complex factors prevent its global elimination. Part of the difficulty in developing optimal therapies is the large design space of antibiotic doses, regimens and combinations. Computational models that capture the spatial and temporal dyna...

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Veröffentlicht in:J Theor Biol
Hauptverfasser: Pienaar, Elsje, Cilfone, Nicholas A., Lin, Philana Ling, Dartois, Véronique, Mattila, Joshua T., Butler, Russ, Flynn, JoAnne L., Kirschner, Denise E., Linderman, Jennifer J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332617/
https://ncbi.nlm.nih.gov/pubmed/25497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.11.021
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