Loading...

Glycosylated Neurotensin Analogs Exhibit the Subpicomolar Anticonvulsant Potency in the Pharmacoresistant Model of Epilepsy

Neurotensin (NT) is an endogenous neuropeptide involved in a variety of central and peripheral neuromodulatory effects. Here we show effects of site-specific glycosylation on the in vitro and in vivo pharmacological properties of this neuropeptide. NT analogs containing O-linked disaccharides (β-mel...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ChemMedChem
Main Authors: Lee, Hee-Kyoung, Zhang, Liuyin, Smith, Misty D., White, H. Steve, Bulaj, Grzegorz
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332545/
https://ncbi.nlm.nih.gov/pubmed/19173215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200800421
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!