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Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress
Reduced signalling through the insulin/insulin-like growth factor-1 signalling (IIS) pathway is a highly conserved lifespan determinant in model organisms. The precise mechanism underlying the effects of the IIS on lifespan and health is currently unclear, although cellular stress resistance may be...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Aging Cell |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BlackWell Publishing Ltd
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331740/ https://ncbi.nlm.nih.gov/pubmed/25059507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12255 |
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