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Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

Reduced signalling through the insulin/insulin-like growth factor-1 signalling (IIS) pathway is a highly conserved lifespan determinant in model organisms. The precise mechanism underlying the effects of the IIS on lifespan and health is currently unclear, although cellular stress resistance may be...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Aging Cell
मुख्य लेखकों: Page, Melissa M, Sinclair, Amy, Robb, Ellen L, Stuart, Jeffrey A, Withers, Dominic J, Selman, Colin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331740/
https://ncbi.nlm.nih.gov/pubmed/25059507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12255
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