Melanocortin Antagonist Tetrapeptides with Minimal Agonist Activity at the Mouse Melanocortin-3 Receptor

Lignende værker

• Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) Modified at the Para Position of the Benzyl Side Chain (DPhe): Importance for Mouse Melanocortin-3 Receptor Agonist versus Antagonist Activity
  af: Proneth, Bettina, et al.
  Udgivet: (2008)
• Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
  af: Ericson, Mark D., et al.
  Udgivet: (2020)
• Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa(1)-Arg-(pI)DPhe-Xaa(4)-NH(2)
  af: Doering, Skye R., et al.
  Udgivet: (2017)
• Structure-Activity Relationships of Peptides Incorporating a Bioactive Reverse-Turn Heterocycle at the Melanocortin Receptors: Identification of a 5,800-fold Mouse Melanocortin-3 Receptor (mMC3R) Selective Antagonist/Partial Agonist versus the Mouse Melanocortin-4 Receptor (mMC4R)
  af: Singh, Anamika, et al.
  Udgivet: (2013)
• Structure–Activity Relationships of the Tetrapeptide Ac-His-Arg-(pI)DPhe-Tic-NH(2) at the Mouse Melanocortin Receptors: Modification at the (pI)DPhe Position Leads to mMC3R Versus mMC4R Selective Ligands
  af: Schlasner, Katherine N., et al.
  Udgivet: (2019)