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Melanocortin Antagonist Tetrapeptides with Minimal Agonist Activity at the Mouse Melanocortin-3 Receptor

[Image: see text] The melanocortin system regulates many important functions in the body. There are five melanocortin G protein-coupled receptor subtypes known to date. Herein, we report a structure–activity relationship (SAR) study of a tetrapeptide lead discovered through a double substitution str...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Doering, Skye R., Todorovic, Aleksandar, Haskell-Luevano, Carrie
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329596/
https://ncbi.nlm.nih.gov/pubmed/25699138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500340z
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