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Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) Modified at the Para Position of the Benzyl Side Chain (DPhe): Importance for Mouse Melanocortin-3 Receptor Agonist versus Antagonist Activity

The melanocortin-3 and -4 receptors (MC3R, MC4R) have been implicated in energy homeostasis and obesity. Whereas the physiological role of the MC4R is extensively studied, little is known about the MC3R. One caveat is the limited availability of ligands that are selective for the MC3R. Previous stud...

詳細記述

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書誌詳細
主要な著者: Proneth, Bettina, Pogozheva, Irina D., Portillo, Federico P., Mosberg, Henry I., Haskell-Luevano, Carrie
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896811/
https://ncbi.nlm.nih.gov/pubmed/18800761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800291b
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